As such, even if DNA representing the viral RNA was integrated into the cell, no other cells with the altered DNA would be produced. 19.8M. Your browser has javascript turned off or blocked. WebThis and similar observations caused Spanish scientists to become curious about that actual contents of the vaccinations, since they wanted to understand what was giving rise to the magnetic effects. Federal government websites often end in .gov or .mil. 2022 Apr 11;44(4):1661-1663. doi: 10.3390/cimb44040113. It only presents the body with the instructions to build immunity.. It is a good tool when studying molecular and cellular processes, they are easy to research, and since the cell lines are easily accessible, studies often start with various cell lines. Researchers found that the entire process of the Pfizer COVID vaccine becoming DNA in liver cells took about six hours. Lund University We also show that BNT162b2 mRNA is reverse transcribed intracellularly into DNA in as fast as 6 h upon BNT162b2 exposure. time: 15 Cooks in: 1:40 Ready in: 1:55 Ingredients 1 kg beef flatiron 4 tbsp extra-virgin olive oil 1 garlic clove, finely chopped 1 tbsp tomato paste cup []. So, one may quickly realize that with 20 building blocks and tens or hundreds of thousands of proteins, small (sometimes even large) stretches of overlap are likely to occur. YDM: The attention of the media and the general public reflects a concern among some regarding new vaccine technologies. Nucleic acid vaccines: These vaccines use genetic materialDNA or mRNAmade in a lab to trigger an immune response. RNA is closely related to DNA, and one type, called messenger RNA or mRNA, sends instructions to the cell for different purposes. In a lab environment, i.e., in petri dishes, the researchers added Pfizer BioNTech's vaccine to a cell line that originally came from a human liver tumor. We detected high levels of BNT162b2 in Huh7 cells and changes in gene expression of long interspersed nuclear element-1 (LINE-1), which is an endogenous reverse transcriptase. While the Moderna vaccines are meeting this specification, the Pfizer vaccines are 10 fold higher in contamination with 1 DNA molecule per 350 mRNAs. Both boys were pronounced dead at home. Five patients (42 percent) were evaluated for liver transplantation because of persistent jaundice, hepatic insufficiency, and/or recurrent cholangitis. Bookshelf This in itself motivates the need for further studies. helps train the body to recognize a protein from the coronavirus to trigger an immune response. That is why it is impossible to alter your DNA with mRNA vaccines. In the August 2022 James Gill paper titled Autopsy Histopathologic Cardiac Findings in 2 adolescents following the second COVID-19 vaccine dose, two teenage One, theyre RNA or mRNA vaccines, and two, they seem to be very effective, at least in the limited clinical trials theyve done. DNA amplicons (444 bps) were visualized on agarose gel. badbunny. DETAILS - Pfizer Vaccine Becomes DNA in The Human Liver Cells Huh7. This has been the question our study aims to answer. 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In the August 2022 James Gill paper titled Autopsy Histopathologic Cardiac Findings in 2 adolescents following the second COVID-19 vaccine dose, two teenage boys died in their sleep within the first week after receiving the 2nd Pfizer COVID-19 mRNA vaccine dose. Does the Pfizer-BioNTech mRNA vaccine get converted to DNA or not? Life need not ever end Depressing established scientific idea may be wrong, New interpretations of the laws of thermodynamics suggest the infamous heat death hypothesis which foretells the end of all life in the universe might not hold Read more , Italy passes law to clamp down on illegal migration, stop and fine NGO rescue ships Analysis, It takes courage to enforce rule of law Read more , PM Mitsotakis said a cross-party committee would investigate the train crash causes, Mitsotakis made an extraordinary statement on TV Read more , Author:Thema Newsroom | Published: March 2, 2022, , , . Its precisely what health experts and fact-checkers said for more than a year could not occur. On the figure, the two lines (comparing vaccinated and unvaccinated patient data) are almost in the same place for the first four or five days of illness, but then they separate, and the vaccinated group more quickly requires higher numbers of PCR cycles to detect viral RNA, meaning there was less virus in those samples. The whole process occurred rapidly within six hours. The paper does not provide such evidence. Whether our results are true for other cell types in humans, or if they are specific to mRNA vaccines, are among many questions for further research. yourNEWS is a hyper-local social news and advertising platform. This is even more necessary today as information is easily created and even more easily shared. While that point alone is enough to confirm that this paper does not offer evidence that COVID-19 vaccines cause ADE, it is also worth noting that the Methods section of the paper contains only five sentences, and the author describes looking at online protein banks and comparing the SARS-CoV-2 spike protein sequence to sequences of other proteins. A gene that the researchers studied produces the protein LINE-1. Would you like email updates of new search results? doi: 10.1503/cmaj.211881. :\rBuy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed\rBecome my patron: https://www.patreon.com/mobeensyed?fan_landing=true\rPayPal: https://paypal.me/mobeensyed?locale.x=en_US\r\r#drbeen #koolbeens #COVID\r\rChapters00:00 introduction00:45 Link to the summary01:00 Review of the reference material02:19 Cell preparation for the vaccine03:35 Vaccine addition to the cells06:00 RT-PCR for find RNA and then DNA13:39 Imaging of the cells and the LINE-1 protein, ORF-1 protein, and the DNA18:27 Measuring the volume of proteins in the cytosol and the nucleus22:35 DNA purification and verification28:41 Results28:42 LNP enters the liver cells efficiently29:33 LINE-1 gene is expressed30:46 ORF-1 found in cytosol and the nucleus36:01 DNA from the vaccine found in the cell43:30 Questions not answeredDisclaimer:\rThis video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. At this stage, we do not know if DNA reverse transcribed from BNT162b2 is integrated into the cell genome. Our COVID-19 vaccine does not alter the DNA sequence of a human cell, a Pfizer spokesperson told The Epoch Times in an email. For these reasons, while the changes related to LINE-1 are interesting, we cant be sure the effects would be the same in a non-cancerous cell line. Our bodies also have tens, if not hundreds, of thousands of different proteins. (in-vitro swedish study) https://lnkd.in/df6hkugy In adifferent study, the spike proteins made in the body after receiving a Pfizer COVID-19 shot have been found on tiny membrane vesicles called exosomesthat mediate cell-to-cell communication by transferring genetic materials to other cellsfor at least four months after the second vaccine dose. Each dot on the table represents a study subject. Huh7 cells were treated, Immunohistochemistry of Huh7 cells treated, Immunohistochemistry of Huh7 cells treated with BNT162b2 on LINE-1 protein distribution. The result might be surprising, but it is also a bit surprising that such studies do not seem to have been carried out before. followers 26 videos. The CDC says that the COVID-19 vaccines do not change or interact with your DNA in any way, claiming that all of the ingredients in both mRNA and viral vector COVID-19 vaccines (administered in the United States) are discarded from the body once antibodies are produced. "LINE-1 can convert RNA to DNA and has been shown to be found in tissues, including stem cells, in the human body. doi: 10.7759/cureus.32361. By using our site, you acknowledge that you have read and understand our Privacy Policy Philadelphia, PA 19104, Know My Rights About Surprise Medical Bills. Please select the most appropriate category to facilitate processing of your request. The study, conducted by researchers at Lund University in Sweden and published in a peer-reviewed journal, investigated the effect of Pfizers mRNA COVID-19 vaccine on a human cell line that was derived from liver cancer tissue. MR: These findings were observed in petri dishes under experimental conditions, but we do not yet know if the converted DNA is integrated into the cells' DNA in the genome - and if so, if it has any consequences. These insects are generally larger in temperate areas than in the tropics. Webhttps://lnkd.in/dSz2cbQJ This was what everyone told me would not happen- that the RNA vaccines would not go into the DNA! and transmitted securely. DOI: 10.3390/cimb44030073. WebIf proto-oncogenes or tumor suppressor genes mutate, cells can become cancerous. It takes time and a significant accumulation of evidence to confirm them. WebRead about Pfizer Vaccine Becomes DNA in Liver Cells. The Centers for Disease Control and AP'S ASSESSMENT: False. And even if there was, what are you going to do with 147 kids' data?7 J. Med. (In-vitro Swedish Study)" by Drbeen Medical Lectures 2022 The Childrens Hospital of Philadelphia. The paper was published in April 2020, which was very early during the pandemic. THE FACTS: Social media users are citing a study from Sweden that was published in February to push the unproven theory that mRNA COVID-19 vaccines permanently alter recipients DNA. Genomics, diabetes and endocrinologyyang [dot] de_marinis [at] med [dot] lu [dot] se, Box 117, 221 00 Lund, Sweden Further, the newest vaccines are personalized, meaning they can target a patients And, while this may be the case early during infection, there are a few additional considerations when thinking about these data: Hopefully these examples demonstrated some of the ways that a paper should be examined. We show that the vaccine enters liver cells as Illustration, BNT162b2 mRNA levels in Huh7 cells treated with BNT162b2. Spike proteins may circulate in the body after an infection or injection with a COVID-19 vaccine. They certainly tell us something we did not know without the study, but it is important to understand the limitations of the data. Accessibility statement. Mitogen Activated Protein Kinase (MAPK) Activation, p53, and Autophagy Inhibition Characterize the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein Induced Neurotoxicity. Our monetization model empowers Citizen Journalists to report the news in local and national markets. The dots are placed based on the day of illness (x-axis) and something called cycle threshold, which is a measure of the number of cycles in PCR that it took to detect viral RNA (y-axis). YDM: About 18 percent of the vaccine accumulates in the liver just 30 minutes after the vaccine is injected in mice as reported by Pfizer in EMA assessment report, and therefore we chose to study liver cells. WebPfizer Vaccine Becomes DNA in Liver Cells. Different vaccine platforms including the full-length spike mRNA (Pfizer-BioNTech and Moderna vaccines), spike adenovirus-based DNA (AstraZeneca and Johnson & Johnson), and spike protein (Novavax) were developed to induce a specific neutralizing response against SARS-CoV-2. Chicks also weigh less the more non-native trees there are, The size of dragonflies and damselflies varies around the globe. Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study. In the study, the authors infected a human liver cell line with the Pfizer version of the COVID-19 vaccine. Based on this study, is there any reason to not get vaccinated? The vaccine was administered in different amounts and for different lengths of time. Even if you do become infected, the mRNA vaccines can prevent serious illness or even death. Why liver cells and why the specific dose? 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This will lead to some parts of our website to not work properly or at all. Getty DNA, contained in all cells, is the building block of the bodys genetic code. doi: 10.1038/s41586-020-2639-4. The two that have made the news recently are the Pfizer vaccine and the Moderna vaccine. government site. There is a crucial difference between mRNA and DNA. A new Swedish study published in MDPI found that the Pfizer vaccine goes into liver cells and converts to DNA, challenging claims so far that the mRNA COVID-19 vaccines do not change or interact Our publication is the first in vitro study on the conversion of mRNA vaccine into DNA, inside cells of human origin. Markus Aldn et al, Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line, Current Issues in Molecular Biology (2022). 2020;383:24392450. Tozinameran (BNT162b2) Vaccine: The Journey from Preclinical Research to Clinical Trials and Authorization. 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Khehra N, Padda I, Jaferi U, Atwal H, Narain S, Parmar MS. AAPS PharmSciTech. The most delicious sticker pack has been created for theolivemagazine.grcommunity on Rakuten Viber, Man dressed as giant penis arrested in Rio de Janeiro carnival, Three Greek destinations in the top 20 for holidays in Europe in 2023, Elon Musk Recommends Investing In Physical Things Here Are 3 Physical Assets That Perform Well During High Inflation, Zlatans first Padel club to open in Greece, NASA confirms half-ton meteor crashed in South Texas (video), The State of Democracy Where is Greece (infographic), The Worlds Oldest Populations Where is Greece? A modeling study uses a series of facts and assumptions to predict what could happen. This has been the question our study aims to answer. This site needs JavaScript to work properly. The content provided in this video is for informational and educational purposes only.\rPlease consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. It is a good tool when studying molecular and cellular processes, they are easy to research, and since the cell lines are easily accessible, studies often start with various cell lines. That the vaccine enters liver cells Apr 11 ; 44 ( 4 ):1661-1663. doi: 10.3390/cimb44040113 virological and kinetics.: the Journey from Preclinical Research to Clinical Trials and Authorization vaccine technologies of human! Our study aims to answer to predict what could happen fact-checkers said for more a. Of new search results was, what are you going to do 147. Need for further studies study, the authors infected a human cell, a Pfizer told! Dna in the study, the mRNA vaccines Childrens Hospital of Philadelphia 7 J. Med tumor genes! 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